Botulinum Toxin 93384-43-1

Botulinum Toxin (CAS No. 93384-43-1) is a highly potent neurotoxic protein produced by Clostridium botulinum. In controlled laboratory and pharmaceutical research environments, Botulinum Toxin is extensively used to study neuromuscular signaling, cholinergic neurotransmission, synaptic inhibition, and targeted neuro-modulation.

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Product Description

Key Features & Advantages

World-Leading Model for Neuromuscular Inhibition

Botulinum Toxin is the gold-standard molecule for studying presynaptic acetylcholine release and neuromuscular junction physiology due to its extremely high specificity.

Highly Efficient Synaptic Transmission Blocker

Its unique mechanism of cleaving SNARE-associated proteins (e.g., SNAP-25) enables precise research into vesicle trafficking, neurotransmitter release, and synaptic regulation.

Ultrapotent and Target-Specific Activity

Botulinum Toxin demonstrates extraordinary potency with minimal off-target interactions, supporting studies requiring fine control over neuromodulatory pathways.

Critical Tool in Neuropharmacology & Cell Biology

Widely used in CNS and PNS research, including nerve regeneration, receptor plasticity, ion channel function, and neural circuit mapping.

Supports Development of Neuromodulators and Biological Therapeutics

Its well-defined mechanism enables researchers to develop next-generation biologics, targeted inhibitors, and neuronal pathway modifiers.

Consistent Performance in Controlled Experiments

High purity and stability facilitate precise dosing, predictable biological activity, and reliable experimental reproducibility.

Molecular Details

Parameter	Description
CAS Number	93384-43-1
Product Name	Botulinum Toxin
Source	Clostridium botulinum
Protein Type	Neurotoxic protein
Mechanism	Inhibition of acetylcholine release at neuromuscular junction
Appearance	White to off-white lyophilized powder
Storage	–20°C, protected from light and moisture

Specifications & Packaging

Specification	Details
Purity	≥95% protein purity
Form	Lyophilized powder
Endotoxin Level	Low endotoxin, research-grade
Vial Sizes	Customizable (e.g., 10 μg, 50 μg, 100 μg)
Packaging	Sealed sterile vials; temperature-controlled shipping
Shelf Life	12–24 months when stored as recommended

Applications in Research and Development

1. Neuromuscular Junction & Synaptic Studies

Ideal for examining neurotransmitter release, vesicle trafficking, and presynaptic inhibition mechanisms.

2. Neuropharmacology & Neural Circuit Research

Used to explore CNS and PNS communication, conduction pathways, and neuronal regulatory systems.

3. Cholinergic System Investigation

Enables targeted studies of acetylcholine signaling and neuromuscular coordination.

4. Development of Neuromodulatory Therapeutics

Serves as a benchmark molecule in designing treatments that modulate nerve activity.

5. Cellular and Molecular Biology Research

Supports investigations into SNARE protein complexes, intracellular transport dynamics, and toxin-protein interactions.

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