• PT-141 189691-06-3

  • PT-141 189691-06-3

  • PT-141 189691-06-3

PT-141 189691-06-3

PT-141 (Bremelanotide, CAS No. 189691-06-3) is a synthetic peptide and melanocortin receptor agonist, primarily developed for its effects on sexual function. Unlike traditional treatments, PT-141 acts directly on the central nervous system to stimulate sexual arousal and desire.

Product Description

Key Features & Advantages

 

Enhances Sexual Arousal and Libido

 

PT-141 stimulates melanocortin receptors in the brain, promoting sexual desire in both male and female models. This central action differentiates it from peripheral-targeting therapies and makes it highly relevant in sexual health research.

 

Supports Neuroendocrine Function

 

PT-141 modulates neurohormonal pathways, influencing dopamine, melanocortin, and other neurotransmitter systems that regulate sexual behavior, stress response, and mood.

 

Rapid and Targeted Action

 

Research indicates PT-141 has fast onset effects in preclinical models, with central nervous system activity that bypasses cardiovascular pathways common in other sexual function therapies.

 

Non-Toxic and Research-Grade

 

PT-141 is highly purified, well-characterized, and demonstrates minimal toxicity in experimental settings, suitable for both in vitro and in vivo studies.

 

Potential for Reproductive and Behavioral Studies

 

Beyond sexual health, PT-141 is explored in neuroscience and behavioral research due to its effects on motivational and reward pathways.

 

Molecular Details

 

Parameter Description
CAS Number 189691-06-3
Product Name PT-141 (Bremelanotide)
Molecular Formula C₅₁H₆₉N₁₃O₁₀
Molecular Weight 841.0 g/mol
Amino Acid Sequence Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH
Appearance White to off-white lyophilized powder
Storage Store at –20°C, protected from light

 

Specifications & Packaging

 

Specification Option
Purity ≥98% (HPLC)
Form Lyophilized powder
Vial Sizes 1 mg, 5 mg, 10 mg, 50 mg (custom options available)
Packaging Sterile sealed vials; moisture-resistant, temperature-controlled packaging
Shelf Life 24 months under recommended storage conditions

 

Applications in Research and Development

 

1. Sexual Dysfunction Research

 

PT-141 is widely investigated for its effects on sexual desire, arousal, and reproductive behaviors in preclinical and clinical models.

 

2. Neuroendocrine Studies

 

Its modulation of melanocortin and dopaminergic pathways makes PT-141 valuable for research into neurohormonal regulation and brain signaling mechanisms.

 

3. Behavioral and Motivational Studies

 

PT-141’s effects on reward and motivation systems allow it to be used in neuroscience and behavioral research.

 

4. Reproductive Health Research

 

PT-141 provides a research model for developing therapies targeting male and female sexual dysfunction, hormone-regulated reproductive pathways, and libido enhancement.

 

5. Peptide-Based Therapeutic Development

 

PT-141 serves as a key experimental compound in the development of peptide-based drugs for sexual health, neuroendocrine modulation, and behavioral interventions.