• Sermorelin 86168-78-7

  • Sermorelin 86168-78-7

  • Sermorelin 86168-78-7

Sermorelin 86168-78-7

Sermorelin (CAS No. 86168-78-7) is a synthetic peptide consisting of the first 29 amino acids of endogenous growth hormone–releasing hormone (GHRH). As the biologically active fragment of GHRH, Sermorelin is widely used in endocrine research due to its strong ability to stimulate natural growth hormone secretion from the pituitary gland.

Product Description

Key Features & Advantages

 

Stimulates Natural Growth Hormone Secretion

 

Sermorelin binds to GHRH receptors in the pituitary gland to stimulate physiological growth hormone production, making it invaluable for research involving GH pathways, pituitary function, and hormone regulation.

 

Supports Muscle Growth & Tissue Recovery

 

By enhancing GH release, Sermorelin promotes protein synthesis, muscle repair, and cellular regeneration. It is frequently used in studies of muscle-wasting disorders, post-injury recovery, and anabolic signaling.

 

Enhances Lipolysis & Metabolic Function

 

Growth hormone plays a key role in fat metabolism. Sermorelin is commonly included in research focusing on body composition, lipid oxidation, and metabolic disorders.

 

Promotes Healthy Aging Mechanisms

 

Researchers study Sermorelin for its potential role in anti-aging biology, due to its involvement in improving cellular repair, metabolic vitality, and age-related GH decline.

 

Physiological GH Pulsing Without Excessive Stimulation

 

Unlike non-GHRH peptides, Sermorelin supports natural pulsatile GH release without overstimulation, making it a safe and controlled tool for long-term endocrine studies.

 

Favorable Safety and Tolerability Profile

 

Sermorelin has demonstrated excellent safety in research environments, with low toxicity and minimal adverse reactions under standard laboratory conditions.

 

Molecular Details

 

Parameter Description
CAS Number 86168-78-7
Product Name Sermorelin
Molecular Formula C₁₄₉H₂₄₆N₄₄O₄₂
Molecular Weight 3357.88 g/mol
Amino Acid Sequence H-Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-NH₂
Appearance White to off-white lyophilized powder
Storage Store at –20°C, protected from light

 

Specifications & Packaging

 

Specification Option
Purity ≥98% (HPLC)
Form Lyophilized powder
Vial Sizes 1 mg, 5 mg, 10 mg, 50 mg (customized packaging available)
Packaging Sterile sealed vials; moisture-resistant, temperature-controlled packaging
Shelf Life 24 months under recommended storage conditions

 

Applications in Research and Development

 

1. Growth Hormone Deficiency Studies

 

Sermorelin is a key peptide for modeling and researching pediatric and adult GH deficiency, pituitary function, and hormone regulation mechanisms.

 

2. Musculoskeletal Regeneration Research

 

By supporting GH-mediated tissue repair, Sermorelin is used in studies of muscle regeneration, tendon repair, and injury recovery.

 

3. Metabolic & Obesity Research

 

Its role in modulating lipolysis and metabolic rate makes Sermorelin valuable for research involving obesity, metabolic syndrome, and energy regulation.

 

4. Aging & Cellular Repair Studies

 

Sermorelin is widely used in studies exploring age-related hormonal decline, cellular repair pathways, and longevity research.

 

5. Endocrine Combination Therapy Research

 

Sermorelin is frequently studied in combination with other secretagogues to investigate synergistic GH stimulation and advanced peptide-based drug delivery systems.