Snap-8 868844-74-0

Snap-8 (CAS No. 868844-74-0) is a synthetic peptide analog of Argireline, designed as a short-chain cosmetic peptide with anti-wrinkle and skin-smoothing properties. Composed of eight amino acids, Snap-8 targets the neuromuscular signaling pathway by modulating SNARE complex proteins, which reduces the release of neurotransmitters responsible for facial muscle contraction.

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Product Description

Key Features & Advantages

Reduces Facial Muscle Contraction

Snap-8 inhibits neurotransmitter release by interfering with the SNARE complex, leading to decreased dynamic wrinkles caused by repetitive facial movements.

Anti-Aging & Wrinkle-Reducing Effects

Preclinical and cosmetic research demonstrates its potential to reduce the appearance of fine lines and improve skin elasticity and firmness.

Safe Peptide for Topical Use

Snap-8 is non-toxic and well-tolerated in topical formulations, making it ideal for skin care research and cosmetic product development.

Enhanced Stability Compared to Argireline

Snap-8 features chemical modifications that improve its stability, potency, and penetration in skin models relative to traditional hexapeptide analogs.

Supports Cosmetic & Dermatology Research

Widely used in studies on peptide-based skincare, anti-aging formulations, and neuromodulator alternatives for facial aesthetics.

Molecular Details

Parameter	Description
CAS Number	868844-74-0
Product Name	Snap-8
Molecular Formula	C₄₈H₈₈N₁₄O₁₂
Molecular Weight	887.03 g/mol
Amino Acid Sequence	Ac-Glu-Glu-Met-Gln-Arg-Arg-Ala-Ala-NH₂
Appearance	White to off-white lyophilized powder
Storage	–20°C, protected from light and moisture

Specifications & Packaging

Specification	Option
Purity	≥98% (HPLC)
Form	Lyophilized powder
Vial Sizes	1 mg, 5 mg, 10 mg (custom sizes available)
Packaging	Sterile sealed vials, moisture-resistant, temperature-controlled
Shelf Life	24 months under recommended storage conditions

Applications in Research and Development

1. Cosmetic & Anti-Wrinkle Research: Studying the reduction of dynamic wrinkles, skin smoothness, and elasticity in vitro and in ex vivo skin models.

2. Neuromuscular Signaling Studies: Snap-8 serves as a research tool for investigating SNARE complex modulation and neurotransmitter release pathways.

3. Peptide-Based Cosmetic Formulation Development: Used in testing new topical products or delivery systems aimed at anti-aging, facial rejuvenation, and skin firming.

4. Alternative to Botox-Like Effects: Its mild neuromodulatory effect makes Snap-8 an attractive research molecule for safer alternatives to injectable neurotoxins in cosmetic science.

5. Dermatology & Skin Biology Studies: Supports studies on skin penetration, peptide stability, and bioactive delivery in dermatological research.

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