CJC-1295 DAC 154947-66-7

CJC-1295 DAC (CAS No. 154947-66-7) is a synthetic growth hormone-releasing hormone (GHRH) analog engineered with Drug Affinity Complex (DAC) technology to extend its half-life in circulation. By stimulating the pituitary gland to secrete growth hormone (GH), CJC-1295 DAC promotes IGF-1 production, tissue growth, and cellular regeneration.

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Product Description

Key Features & Advantages

Extended Half-Life via DAC Technology

CJC-1295 DAC binds to circulating albumin, extending its plasma half-life to approximately 6–8 days, allowing less frequent dosing in experimental models.

Stimulates Growth Hormone (GH) Secretion

Effectively increases pulsatile GH release, which in turn elevates insulin-like growth factor-1 (IGF-1) levels, supporting studies of growth, metabolism, and tissue repair.

Supports Muscle & Tissue Regeneration Research

By promoting GH/IGF-1 axis activity, it facilitates investigations into skeletal muscle hypertrophy, tendon repair, and connective tissue regeneration.

Potential Anti-Aging Applications

CJC-1295 DAC is frequently used in research on age-related decline in GH production, helping to study metabolism, body composition, and cellular rejuvenation.

High Stability & Research Consistency

Lyophilized, purified form ensures reproducible activity in vitro and in vivo, making it suitable for long-term experimental studies.

Molecular Details

Parameter	Description
CAS Number	154947-66-7
Product Name	CJC-1295 DAC
Molecular Formula	C₁₀₁H₁₆₆N₃₂O₂₀
Molecular Weight	4,329.08 Da
Amino Acid Sequence	Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-NH₂
Appearance	White to off-white lyophilized powder
Storage	–20°C, protected from light and moisture

Specifications & Packaging

Specification	Option
Purity	≥98% (HPLC)
Form	Lyophilized powder
Vial Sizes	1 mg, 2 mg, 5 mg, 10 mg (custom packaging available)
Packaging	Sterile sealed vials, moisture-resistant, temperature-controlled
Shelf Life	24 months under recommended storage conditions

Applications in Research and Development

1. Endocrinology & GH Axis Research: Used to study growth hormone regulation, IGF-1 signaling, and pituitary gland function.

2. Muscle Growth & Regeneration Studies: Supports research on skeletal muscle hypertrophy, connective tissue repair, and rehabilitation models.

3. Metabolic & Anti-Aging Research: Explores effects on body composition, fat metabolism, and age-related decline in GH secretion.

4. Tissue Repair & Regenerative Medicine: Facilitates research in wound healing, tendon regeneration, and cellular growth processes.

5. Peptide Therapeutic Development: Serves as a model for designing long-acting GHRH analogs and sustained-release peptide therapeutics.

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