• TB-500 77591-33-4

  • TB-500 77591-33-4

TB-500 77591-33-4

TB-500 (CAS No. 77591-33-4) is a synthetic peptide derived from the naturally occurring protein thymosin beta-4. Comprising 43 amino acids, TB-500 is widely studied for its powerful tissue repair, anti-inflammatory, and regenerative properties.

Product Description

Key Features & Advantages

 

Accelerates Tissue Repair and Regeneration

 

TB-500 facilitates the repair and regeneration of muscle, tendon, ligament, and connective tissues. By promoting cellular migration and proliferation, it supports faster healing of injuries and reduces recovery time in preclinical models.

 

Enhances Angiogenesis

 

TB-500 stimulates the formation of new blood vessels, improving oxygen and nutrient delivery to damaged tissues. This angiogenic effect is critical for wound healing, tissue regeneration, and recovery after trauma or surgery.

 

Reduces Inflammation

 

TB-500 exhibits potent anti-inflammatory properties, helping to decrease swelling, pain, and tissue damage in both acute and chronic injury models. This makes it valuable for studies on soft tissue injuries and inflammatory conditions.

 

Supports Hair Follicle and Skin Repair

 

Studies suggest TB-500 may improve skin elasticity, promote hair growth, and accelerate wound closure, highlighting its potential in dermatological and cosmetic research.

 

Safe and Well-Tolerated

 

TB-500 is known for its low toxicity profile, even at higher concentrations, making it suitable for long-term experimental and therapeutic applications compared to other peptides.

 

Molecular Details

 

Parameter Description
CAS Number 77591-33-4
Product Name TB-500
Molecular Formula C₁₈₆H₂₉₁N₅₅O₆₉S
Molecular Weight 4963.57 g/mol
Amino Acid Sequence Ac-Ser-Asp-Lys-Pro-Val-Thr-Lys-Phe-Lys-Lys-Glu-Lys-Glu-Asp-Lys-Ala-Lys-Lys-Glu-Leu-Thr-Asp-Lys-Glu-Lys-Lys-Leu-Glu-Lys-Lys-Glu-Leu-Thr-Asp-Lys-Glu-Lys-Lys-Leu-OH
Appearance White to off-white lyophilized powder
Storage Store at –20°C, protected from light

 

Specifications & Packaging

 

Specification Option
Purity ≥98% (HPLC)
Form Lyophilized powder
Vial Sizes 2 mg, 5 mg, 10 mg, 50 mg (custom options available)
Packaging Sterile sealed vials; moisture-resistant, temperature-controlled packaging
Shelf Life 24 months under recommended storage conditions

 

Applications in Research and Development

 

1. Wound Healing & Tissue Regeneration

 

TB-500 is widely studied for accelerating healing after injuries, surgeries, or chronic tissue damage, including tendon and ligament repair.

 

2. Musculoskeletal Injury Recovery

 

Its effects on cell migration and collagen synthesis make TB-500 a key peptide for musculoskeletal injury research, including tendonitis, ligament tears, and muscle strain recovery.

 

3. Anti-Inflammatory Research

 

TB-500's ability to reduce inflammation and promote tissue repair is valuable for studying soft tissue injuries, chronic inflammatory diseases, and trauma recovery.

 

4. Dermatology & Hair Growth Research

 

TB-500 is explored for applications in skin repair, wound closure, and hair follicle regeneration due to its effects on cellular migration and tissue remodeling.

 

5. Regenerative Medicine & Drug Development

 

TB-500 is an important molecule in the development of regenerative therapies and peptide-based drug delivery systems targeting damaged tissues.